Pat Wheelan: search on Z-Library

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1

Imidazopyridine-5,6,7,8-tetrahydro-8-quinolinamine derivatives with potent activity against HIV-1

Kristjan S. Gudmundsson, Sharon D. Boggs, John G. Catalano, Angilique Svolto, Andrew Spaltenstein, Michael Thomson, Pat Wheelan, Stephen Jenkinson

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 1.35 MB

english, 2009

2

Metabolism of Leukotriene B4 (LTB4) and 12-Hydroxy-5,8,10,14-Eicosatetraenoic Acid (12-HETE) in Human Keratinocytes

PAT WHEELAN, JEFFREY B. TRAVERS, JOSEPH G. MORELLI, ROBERT C. MURPHY

Journal:

Annals of the New York Academy of Sciences

Year:

1994

Language:

english

File:

PDF, 506 KB

english, 1994

3

ChemInform Abstract: Discovery of a Novel Series of Cyclic Urea as Potent CCR5 Antagonists.

Maosheng Duan, Wieslaw M. Kazmierski, Matt Tallant, Jung Ho Jun, Mark Edelstein, Rob Ferris, Dan Todd, Pat Wheelan, Zhiping Xiong

Journal:

Year:

2012

File:

PDF, 22 KB

2012

4

Electrospray ionization and low energy tandem mass spectrometry of polyhydroxy unsaturated fatty acids

Pat Wheelan, Joseph A. Zirrolli, Robert C. Murphy

Journal:

Journal of the American Society for Mass Spectrometry

Year:

1996

Language:

english

File:

PDF, 1.02 MB

english, 1996

5

Metabolism of 6- trans -Isomers of Leukotriene B 4 in Cultured Hepatoma Cells and in Human Polymorphonuclear Leukocytes

Wheelan, Pat, Murphy, Robert C.

Journal:

Journal of Biological Chemistry

Year:

1995

File:

PDF, 1.28 MB

1995

6

Negative ion electrospray tandem mass spectrometric structural characterization of leukotriene B4(LTB4) and LTB4-derived metabolites

Pat Wheelan, Joseph A. Zirrolli, Robert C. Murphy

Journal:

Journal of the American Society for Mass Spectrometry

Year:

1996

Language:

english

File:

PDF, 1014 KB

english, 1996

7

Novel N-substituted benzimidazole CXCR4 antagonists as potential anti-HIV agents

John F. Miller, Elizabeth M. Turner, Kristjan S. Gudmundsson, Stephen Jenkinson, Andrew Spaltenstein, Michael Thomson, Pat Wheelan

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 536 KB

english, 2010

8

Discovery of N-benzyl-N′-(4-pipyridinyl)urea CCR5 antagonists as anti-HIV-1 agents (II): Modification of the acyl portion

Maosheng Duan, Jennifer Peckham, Mark Edelstein, Robert Ferris, Wieslaw M. Kazmierski, Andrew Spaltenstein, Pat Wheelan, Zhiping Xiong

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 255 KB

english, 2010

9

Discovery of a novel series of cyclic urea as potent CCR5 antagonists

Maosheng Duan, Wieslaw M. Kazmierski, Matt Tallant, Jung Ho Jun, Mark Edelstein, Rob Ferris, Dan Todd, Pat Wheelan, Zhiping Xiong

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 587 KB

english, 2011

10

Identification of Novel Metabolites of Prostaglandin E2Formed by Isolated Rat Hepatocytes

Joseph A. Hankin, Pat Wheelan, Robert C. Murphy

Journal:

Archives of Biochemistry and Biophysics

Year:

1997

Language:

english

File:

PDF, 277 KB

english, 1997

11

[2-(4-Phenyl-4-piperidinyl)ethyl]amine based CCR5 antagonists: derivatizations at the N-terminal of the piperidine ring

Maosheng Duan, Christopher Aquino, Robert Ferris, Wieslaw M. Kazmierski, Terry Kenakin, Cecilia Koble, Pat Wheelan, Chris Watson, Michael Youngman

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 1.67 MB

english, 2009

12

The reactions of [tris(trimethylsilyl)methyl] diphenylbromosilane and tetra-n-butylphosphonium chloride

R. Damrauer, Pat Wheelan, H. Razavi, M. Whalen, L. Aran

Journal:

Inorganica Chimica Acta

Year:

1985

Language:

english

File:

PDF, 550 KB

english, 1985

13

3-Hydroxyleukotriene B4 (3-OH-LTB4): Total Synthesis and Stereochemical Assignment.

Bhatt, Rama K., Chauhan, Kamlesh, Wheelan, Pat, Falck, J. R., Murphy, Robert C.

Journal:

Journal of the American Chemical Society

Year:

1994

Language:

english

File:

PDF, 936 KB

english, 1994

14

Low-energy fast atom bombardment tandem mass spectrometry of monohydroxy substituted unsaturated fatty acids

Pat Wheelan, Joseph A. Zirrolli, Robert C. Murphy

Journal:

Biological Mass Spectrometry = Journal of Mass Spectrometry (Wiley)

Year:

1993

Language:

english

File:

PDF, 732 KB

english, 1993

15

Analysis of long-chain fatty acyl coenzyme a thioesters by negative ion fast-atom bombardment mass spectrometry and tandem mass spectrometry

Joseph A. Zirrolli, Pat Wheelan, Robert C. Murphy

Journal:

Journal of the American Society for Mass Spectrometry

Year:

1994

Language:

english

File:

PDF, 779 KB

english, 1994

16

Gas Chromatographic/Mass Spectrometric Analysis of Oxo and Chain-shortened Leukotriene B4 Metabolites. Leukotriene B4 Metabolism in Ito Cells

Wheelan, Pat, Murphy, Robert C., Simon, Francis R.

Journal:

Journal of Mass Spectrometry

Year:

1996

Language:

english

File:

PDF, 860 KB

english, 1996

17

Synthesis and antiviral activities of novel N-alkoxy-arylsulfonamide-based HIV protease inhibitors

Ronald G. Sherrill, Eric S. Furfine, Richard J. Hazen, John F. Miller, David J. Reynolds, Douglas M. Sammond, Andrew Spaltenstein, Pat Wheelan, Lois L. Wright

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 180 KB

english, 2005

18

4,4-Disubstituted Cyclohexylamine based CCR5 Chemokine Receptor Antagonists as Anti-HIV-1 agents

Maosheng Duan, Wieslaw Kazmierski, Christopher Aquino, Rob Ferris, Terry Kenakin, Chris Watson, Pat Wheelan

Journal:

Antiviral Research

Year:

2009

Language:

english

File:

PDF, 164 KB

english, 2009

19

Decarboxylation of peptide-bound aminomalonic acid

Wheelan, Pat, Kirsch, Wolff M., Koch, Tad H.

Journal:

Journal of Organic Chemistry

Year:

1989

Language:

english

File:

PDF, 1023 KB

english, 1989

20

Discovery of novel pyridyl carboxamides as potent CCR5 antagonists and optimization of their pharmacokinetic profile in rats

Maosheng Duan, Wieslaw M. Kazmierski, Pek Y. Chong, Felix DeAnda, Mark Edelstein, Rob Ferris, Jennifer Peckham, Pat Wheelan, Zhiping Xiong, Huichang Zhang, Rena Nishizawa, Yoshikazu Takaoka

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 447 KB

english, 2011

21

Analysis of hydroxy fatty acids as pentafluorobenzyl ester, trimethylsilyl ether derivatives by electron ionization gas chromatography/mass spectrometry

Pat Wheelan, Joseph A. Zirrolli, Robert C. Murphy

Journal:

Journal of the American Society for Mass Spectrometry

Year:

1995

Language:

english

File:

PDF, 961 KB

english, 1995

22

Synthesis and SAR of novel isoquinoline CXCR4 antagonists with potent anti-HIV activity

John F. Miller, Kristjan S. Gudmundsson, Leah D’Aurora Richardson, Stephen Jenkinson, Andrew Spaltenstein, Michael Thomson, Pat Wheelan

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 687 KB

english, 2010

23

Synthesis of a novel tricyclic 1,2,3,4,4a,5,6,10b-octahydro-1,10-phenanthroline ring system and CXCR4 antagonists with potent activity against HIV-1

John G. Catalano, Kristjan S. Gudmundsson, Angilique Svolto, Sharon D. Boggs, John F. Miller, Andrew Spaltenstein, Michael Thomson, Pat Wheelan, Doug J. Minick, Dean P. Phelps, Stephen Jenkinson

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 901 KB

english, 2010

24

Synthesis and evaluation of 2-phenyl-1,4-butanediamine-based CCR5 antagonists for the treatment of HIV-1

Matthew D. Tallant, Maosheng Duan, George A. Freeman, Robert G. Ferris, Mark P. Edelstein, Wieslaw M. Kazmierski, Pat J. Wheelan

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 1.66 MB

english, 2011

25

Synthesis and biological evaluation of 14,15-dehydro-LTA4 analog

Mylène Garcia, Thierry Durand, Jean Claude Rossi, Simona Zarini, Manlio Bolla, Giancarlo Folco, Pat Wheelan, Angelo Sala

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 184 KB

english, 1997

26

12-Oxo-LTB4, a Key Pivotal Intermediate in LTB4 Metabolism

Khanapure, Subhash P., Manna, Sukumar, Rokach, Joshua, Murphy, Robert C., Wheelan, Pat, Powell, William S.

Journal:

Journal of Organic Chemistry

Year:

1995

Language:

english

File:

PDF, 1015 KB

english, 1995

27

Discovery of N-benzyl-N′-(4-pipyridinyl)urea CCR5 antagonists as anti-HIV-1 agents (I): Optimization of the amine portion

Maosheng Duan, Jennifer Peckham, Mark Edelstein, Robert Ferris, Wieslaw M. Kazmierski, Andrew Spaltenstein, Pat Wheelan, Zhiping Xiong

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 380 KB

english, 2010

28

Discovery of Bioavailable 4,4-Disubstituted Piperidines as Potent Ligands of the Chemokine Receptor 5 and Inhibitors of the Human Immunodeficiency Virus-1

Kazmierski, Wieslaw M., Aquino, Christopher, Chauder, Brian A., Deanda, Felix, Ferris, Robert, Jones-Hertzog, Deborah K., Kenakin, Terrence, Koble, Cecilia S., Watson, Christian, Wheelan, Pat, Yang, H

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 293 KB

english, 2008

29

Albumin and fatty acid effects on the stimulated production of 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine (PAF) by human polymorphonuclear leukocytes

Pat Wheelan, Keith L. Clay

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1992

Language:

english

File:

PDF, 1.01 MB

english, 1992

30

Free-radical carboxylation of peptide- and protein-bound glycine to form peptide- and protein-bound aminomalonic acid (Ama)

Wheelan, Pat, Kirsch, Wolff M., Koch, Tad H.

Journal:

Journal of Organic Chemistry

Year:

1989

Language:

english

File:

PDF, 714 KB

english, 1989

31

Quantitation of 5-Lipoxygenase Products by Electrospray Mass Spectrometry: Effect of Ethanol on Zymosan-Stimulated Production of 5-Lipoxygenase Products by Human Neutrophils

Pat Wheelan, Robert C. Murphy

Journal:

Analytical Biochemistry

Year:

1997

Language:

english

File:

PDF, 132 KB

english, 1997

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